---
title: "Dose of Alpha Episode #5: A.I. Skills Interview with Taariq Lewis | SerenDB | AlphaGrowth"
description: "They cover the rise of autonomous trading agents, why LLMs are powerful but untrustworthy (\"they lie\"), how AI is the key that finally gets grandma on-chain"
url: "https://alphagrowth.io/blog/dose-of-alpha-episode-5-ai-skills-interview-with-taariq-lewis-serendb/"
---

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Author

Kyril Vlasenko

Podcast

DeFi

1 min read /

6 months ago

# Dose of Alpha Episode #5: A.I. Skills Interview with Taariq Lewis | SerenDB

What if your AI agent could out-trade institutional desks — from your laptop?

In Episode 5 of Dose of Alpha, Bryan Colligan sits down with Taariq Lewis, founder of Seren DB and a crypto OG since 2013, to break down the "Open Claw" world: a future where locally-running AI agents autonomously research, execute, and report on trades — no middlemen, no managed accounts, no waiting on a fund.

They cover the rise of autonomous trading agents, why LLMs are powerful but untrustworthy ("they lie"), how AI is the key that finally gets grandma on-chain, and what happens to knowledge workers when agents don't need sleep.

🔑 Topics covered:

0:00 Intro to Taariq Lewis & Seren DB

1:18 From early crypto to AI Agents

3:19 The Open Claw World explained

6:05 Bypassing UI — bringing non-crypto users onchain

8:30 Skills: AI prompts as functional programs

14:10 Security risks, scams & LLMs lies

18:17 Human displacement by agents

22:31 Agent-to-agent economies & synthetic currencies

26:00 PolyMarket bots & alpha strategies

27:30 Compute-backed currencies

31:30 Smart Beta: shorting SaaS & infrastructure

38:07 Tokenizing skills for non-crypto users

40:44 How to get started with Seren

🌐 Learn more: [**serendb.com**](https://serendb.com/) | 🔗 AlphaGrowth: [**alphagrowth.io**](https://alphagrowth.io/)

📲 Follow Bryan: [**@bryancolligan**](https://x.com/bryancolligan) | [**@alphagrowth1**](https://x.com/alphagrowth1)

The AlphaGrowth team is excited to bring you real-time intel from the DeFi front lines, each week as we release new episodes. Stay tuned for more! And don't forget to comment and share your thoughts with us on [**YouTube**](https://www.youtube.com/@alphagrowth/videos), [**Spotify**](https://open.spotify.com/show/3qrkJE2krg8GhYvRrEVj7L?si=de929349abe14525), [**X**](https://x.com/alphagrowth1), [**Apple Podcasts**](https://podcasts.apple.com/us/podcast/dose-of-alpha/id1878202321)⁠. Bring RWAs onchain with AlphaGrowth in 2026: [**alphagrowth.io⁠**](https://alphagrowth.io/).

Subscribe for more unfiltered DeFi intel, market maneuvers, and alpha drops!

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