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gateway drugs
Recorded: Aug. 29, 2025 Duration: 1:30:51Space Recording
Full Transcription
Thank you. You know what's good? Is it audio working? Yes, it is.
Can you hear me?
Yeah.
We'll get rugged in due time.
Meow.
Always.
We'll give folks some time to join and then we'll kick off.
You should invite some of the speakers up because that'll be...
You know what? I have been. Here we go.
Twitter.
Twitter's already rugged.
Let's see.
Do we big pharma?
Yep.
Raptor.
Cool.
Get some other folks up here.
Yeah.
Get the side out.
Homies up.
Yeah. I sent Jesse a.
Present.
Let's go.
What's good? We're going to talk a lot of Let's go. What's good?
We're going to talk a lot of drugs this space.
More drugs than science for sure.
Good thing I pre-gamed.
It is Friday.
I was loving that it's 420 somewhere.
Yeah, I told everyone like, yeah, we're going to, you know, LSD and psilocybin are launching at 420 and then 420 comes and goes.
Everyone's like, dev got too high.
It wasn't wrong.
It was 420 GMT.
Beautiful.
Which like, if you think about it, that's like the only real 420. But like, what is GMT. Beautiful. Which, like, if you think about it, that's, like, the only real 420.
But, like, what is GMT?
Like, it's just a circle jerk of the English people that, like, oh, our time is time zero.
Actually, there's a Seidaw member who's really into, like, meridian lines.
And I think from what he says it's actually like corresponding to some of
earth's natural way lines
yeah i mean but then again he has english heritage exactly there you go it's like dude it's a sphere
like you can say that the middle is anywhere like you just pick um Anyway. That's kind of what LSD
and psilocybin helped you see as well.
You guys let
Tony be a speaker.
Yeah, I'll get him.
Dude, Tony's not in jail
at this point.
He can still call from jail.
I'll get one call.
Use it on the Twitter space. Oh my God, so epic going in from the jail cell.
Tony, I sent you a request to speak.
Let me know if it didn't come through.
Give me like a thumbs up, thumbs down, maybe.
Trying.
Tony always has problems with his mic.
You know, the jail cell is, they don't get great reception.
Must be one of those bad tales
like Doquan was in in Montenegro.
They extradited him, right?
I think so.
Alright, I don't see him.
I'll try and bring him up when he comes back.
He's in Alcatraz, actually.
They just reopened it for him.
I saw Trump wanted to do that.
Did they change the name of Alcatraz?
I thought it was something ridiculous.
I can't remember.
No, that's the Gulf of Mexico.
Tony.
Tony.
Is he up?
There we go
Board is up
Dude, Tony's back
Back from jail
Still in jail, but calling from jail
Yo, how's this cell?
Not too bad
Who's your roommate?
P. Diddy
And S. Unidentified.
Awesome. All right, let's get going. Jillian, talk to us.
Yes. So I feel like every week we have a space, we come on and say it was a big week and they just keep getting bigger. The on-chain science machine is running, fam. What I thought would be good is we just open up with like a quick recap of honestly, everything that's happened this week.
that really enabled Pump Science
to have a lot of compounds on the platform.
So I thought it would be good to just recap again,
what we've shipped this week,
what folks have shipped this week,
and then invite up some of the drug devs
to, yeah, show their compounds.
But wanna start with some of the things that we've shipped.
Awesome, yeah.
So, I mean, compound wise shipping,
we shipped our, did Raptor and Pioneer launch this week?
Last week.
Oh my God, was that last week?
I don't even know like what day it is anymore.
Properly blacked out.
Yeah. So, I mean, look, like we've launched what, like 50 compounds so far on the platform.
We've launched, what, like 50 compounds so far on the platform.
We have funded like upwards of 40 C. elegans experiments, which are the worms.
I think we've done, I have to go back and count, but it's like, I think almost 15 fly
experiments.
And I think we've done, I think six or seven mouse experiments.
I've gotten funded at this point.
And so honestly, like, it's so fucking sick.
Like we haven't even properly gone viral yet. And already like we're funding a shit ton of research.
So anyway, I'm super freaking bullish on this model. We're going to do some really,
really cool research. We're actually going to produce novel IP and push forward longevity science better than the private markets ever
could. I'm super, I'm getting really, really bullish on this model. The more that I see it
play out. But yeah, so also I think some notable launches were LSD and psilocybin. So Brian
Johnson's been posting a lot about this, but more and more research is just coming out that psychedelics may extend lifespan. It's been validated across
several different like model organisms at this point. And so we're going to kind of test on the
mice. We've got the mice studies funded for LSD and psilocybin already. And so we will do a lifespan study on LSD and psilocybin.
The mice are getting psychedelics.
And we'll see, like, you know, how does that impact their lifespan?
It's freaking crazy.
Like, literally enabled by internet capital markets.
And we will stream it to everybody.
You can see the mice tripping out.
It honestly feels surreal. And then, yeah,
of course, can't forget about the Batty launch. So yeah, we launched Big Pharma in December
with the objective of making it super easy for anyone to launch not just a compound,
but a high quality compound, right? Like one that's real and actually promising, right?
We can obviously submit a ton of garbage
and I'm sure some of it will go viral
because it's ridiculous.
Like somebody launched our soul yesterday
because it sounds like asshole
and then put a picture of an asshole
as their token image.
So like, there's gonna be some of that, but like, I mean, if we really
wanna actually build real long-term value that I hope that people care about
at least a little bit is, uh, is making it easier for anyone to launch a high
quality experiment, uh, on chain.
And so that is what bad is all about.
Um, and so, yeah, basicallydie is all about um and so yeah basically was it yesterday
um yesterday yeah but i literally don't know what that is baddie which is basically yeah
long it's been a long month um so baddie launched it's an llm agent that you can interact with
that will basically give you suggested compounds based on prompts.
So you can say like, what drug will help me live longer? What drug will make my boobs bigger?
What drug will make my dick bigger? What drug will, you know, make my skin darker? Like you
can prompt it with basically any of these, anything you can come up with. There was a guy who literally was in the hospital
because he had kidney stones and he was having terrible pain. And he was using baddie to
come up with how to treat his own pain from the meds that he was getting.
So anyway, it's meant to be like super open. And, you know, you can kind of go down like the drug discovery rabbit hole with it.
And then at the end of it, like you can actually submit compounds to pump science via the agent.
So I think that's that was really like the point at which we were willing to ship it was not just that you'd have a longevity agent to talk to, but that you could actually submit experiments on chain with it.
So anyway, huge shout out to the dev there.
He works on the AI agent team at Google and literally has just been moonlighting,
building baddie and absolutely crushed it.
So huge props to him.
Hopefully we can keep him on, keep him building.
But he shipped this first version.
I'll shut up there. Anything we missed that we wanted to talk about?
Yeah, no, I think just highlighting, obviously, the with Batty, that's really the first,
I would say, like proper agent integration with pump science. But like you said,
what's really cool about it is, instead of going to like Reddit, let's say to like read about,
you know, what compound you should take, you could actually do some research and actually launch an experiment on pump science
and find out. So really, really cool to have that integration and would love to hear from the,
from the big pharma team, like what you've seen. I think you guys properly blew the top off of
pump science yesterday. With that integration integration there was so much traffic it
actually like crashed the site yeah it broke the site we had to upgrade the infrastructure we were
not prepared for that so you had to increase our cup size literally literally boobs broke pump science
yeah that happens that that definitely happens sometimes um Yeah, no, it was great, guys. I think, you know, better than we expected. We still have some work to do. Definitely, we want to, the next step will be, you know, for now, we're just letting people launch compounds using the Big Pharma wallet. And that's kind of like the beta version
just to see how things work.
So we don't get flooded,
but we're planning on very soon
letting anybody do their own dev buy,
which should bring a lot more traction to the platform.
Tony, you want to talk about anything?
Yeah. We're very happy with the first day or so.
Ones being launched are pretty high quality.
Another feature of the platform that wasn't mentioned is
any time the agent mentions a molecule, you can click into
it and see a full readout of the chemical properties and just the characteristics of
that compound. And then of course, launch it directly on pump.science with one click, but we plan on really fleshing out
the ability to dive into the science of any molecule and use that as a
avenue for exploring chemical space, launching better drugs and doing research.
Yeah. Yeah. And, and big shout out to a grumpy.
I know he's here in the space. I hope you're feeling better, bro.
Glad, glad Batty could help. We're just getting started, you know, and,
and, you know, down the line,
we also want to let Batty launch tokenized bio agents in a totally permissionless way.
That is definitely going to take some more work, but that is definitely, you know, one of our big goals on the horizon.
So there's really a lot coming for us.
We have been grinding non-stop in many ways like uh our dev
uh love him great guy uh he is an absolute madman uh engineer and has literally been working all
night long for four months uh to get this out and uh so big props to him and we definitely want to keep him
on the team and uh i think he is down um just have to uh you know get these drugs going and uh
it's going really good so yeah super excited with the launch and uh yeah when when we do release the fully permissionless
i think we're going to see a lot of amazing compounds one one other thing i want to mention
is um this may not be obvious to everybody listening to the space but um the
higher ups that are the more influential folks in the crypto community,
like the founders of some of the exchanges or CEOs of some of the exchanges,
the leaders of Solana and the other L1s, they really want Desai to work.
They really believe in Deci. It's one of very, very few sectors in crypto that actually has traction and is making progress, as we can all see, and is also just doing something good for the world and aligns with big real world narratives that are being changed by AI. And so I would not fade that.
They really believe in Desai.
I think getting behind DeSci is like being on the right side of history.
And I think the influencers in crypto know that and are kind of willing it into existence.
Yeah, 100%.
I mean, sorry, go ahead, Benjels.
No, no, just sorry super quick so i mean look it's not yeah just to kind of riff off what tony said it's not just solana it's everyone in crypto all the
top you know major exchanges i mean if when people ask cz like what are you excited about in crypto
you think he's fucking saying meme coins like Like, obviously not. That's how they pay the bills. But it's not what excites him. Like, what he says excites him is Desai.
We got to talk to the SEC a few days ago, and we explained to them exactly what we're doing.
And they're so aligned. They freaking love this. And because like, I mean, if you think about the new administration, it's all anti-establishment, right? It's like the anti-establishment establishment.
And, you know, you've got the make America healthy again movement. And that aligns so deeply with this deregulation and kind of warm embrace of crypto. They're so bought in.
of crypto they're so bought in um anyway hopefully we'll be meeting hester pierce but uh we'll see
if that happens but yeah we did get to talk to sec and uh they were super excited about this also so
pretty much like anybody you talk to um unless they're evil uh loves these are
yeah yeah and i mean you know even when to, like, the average person on the street, and you're like, what are you excited about with AI?
They say, like, oh, well, I hope it'll, like, cure all diseases and make people healthier and live longer.
Like, that's pretty much everybody's response, even if they, like, this is like the perfect confluence
where like everybody is looking for and rooting for,
you know, it's like even in the like, you know,
end of the world, AI people are like,
oh, everything's gonna end, AI is gonna kill us all,
but maybe it'll cure diseases.
So like this is definitely the spot to be
and really the perfect
opportunity for or not just the crypto space but like the actual real world and like you know
curing cancer and uh saving babies and like this is the real deal yeah and you really want to skate
to where the puck is going not what everyone's talking about right now.
And I think the recent years of kind of capital allocation and winners in both Web2 and Web3 have just been kind of more and more frontier tech, more and more bleeding edge bets. And I think design and AI for bio is next.
100% and just a quick,
a quick ask of people in this space to help spread the DSI, you know,
mission, vision to everybody. I pinned the space tweet at the top. If you could please share
retweets, we can get as many folks in here as possible to hear about all the awesome science
that we're doing. That would be great. And just to kind of build off of that, one thing that we are hoping to do that's a little bit more near term is we are in chats with the Solana team to really try and do a DSI activation at Breakpoint.
So nothing in the books yet, but kind of going back and forth on some ideas.
I'm really hoping to actually bring the science to, uh, to break point in
December. So, um, we're coming out of the lab and into the streets and bringing D site of the people.
So it'll be a lot of fun, but yeah, we have some really cool ideas that we've been going back and
forth on with them too. And it, like you said, it is a big focus for them. A lot of people are
excited about it and want to actually show people the scientific progress that we're doing so um i know bio molecule a lot
of um a lot of the the d site teams are are planning big activations there so it'll be cool
yo jillian will you add uh the nootropics dow guys up please yeah let's do it let me get them up
i'm adding everybody i can find what let's get them up here they're so needy
what let's get them up here they're so needy cool um let's uh let's get the side out squad on guys
congrats on the launch super successful uh talk to us it was good thank you yeah we're we're stoked
um man before psychedelics really came back on the scene in the academic world they were being
talked about on the internet in a very decentralized fashion and a lot of the knowledge
that we know now about them is from these sort of underground chemists and psychonauts that were
just using psychedelics creating psychedelics and talking about psychedelics and just putting data
points up on the internet like an arrowhead blue light and other forums and to see a psychedelic now be launched on a like the
science platform of the future is just uh it's a full circle moment and it's like truly an honor
to be a part of it and to launch these compounds that uh are very much aligned with just a lot of the ethos of the space,
especially right now, just like rebellion, revolution, changing ways of thinking patterns.
So, yeah, Jesse, is there anything you want to add or we can dive into like the science,
the roadmap? There's so many things we have planned for these tokens and we're stoked.
Yeah, Pumsi, I mean, I think what you said highlights that the original DSi on the internet,
the decentralized activity of scientific inquiry, happened mainly in psychedelics. And that the whole
space of DSi owes itself to this origin of those early internet forums like Erowind and Blue Light
and these pioneering biohacker style folks who were experimenting with various psychedelic
chemicals and plants and other there's even psychedelic fish out there they were popular in
Roman times and and to speak to one other thing which is this idea of like the higher-ups
being super bullish on this space, I would say that not only are the higher-ups in crypto
bullish on it, but so are the higher-ups in the universe. That is, these molecules that we deployed yesterday in a head-to-head battle
for the first time in human history, answering an age-old whorl found in Grateful Dead parking lots
and at festivals everywhere between, which is better, LSD or mushrooms. They go way back and they go way
forward. These have been allies of us as a species for such a long time that there are people out
there who think that we owe our faculties of language and tool use to our consumption of these psychedelic molecules.
And so this new inquiry that we're doing here with LSD in silo, tokens, it connects to something
that is very deep-seated in human origins and I we'll have a very important role in the future of humanity.
Just as it's had a very important role in the emergence of Deci,
in the emergence of computer technology, in the emergence of blockchain technology.
You could say that crypto's first product market fit was people buying psychedelics on a silk road.
So yeah, I'm super excited about this.
I'm super excited that we have you as the drug dev because you are a doctor and you literally studied psychedelics and longevity.
Yeah, to speak more on that point too, the stoned egg theory is this theory that we, you know, early humans ate mushrooms and became aware in the universe. And this is sort of a pop
theory, but it's actually been studied in a much more rigorous way, where there's a theory that
humans, as they started becoming more and more integrated social organisms, started experiencing
a serotonin deficit, because serotonin is involved in so many processes related to social environment.
because serotonin is involved in so many processes related to social environment.
And there's a theory that in order to make up for this deficit,
humans found serotonergic agonists in the wild and used them as part of their daily diet and rituals and et cetera.
And that the formation of Homo sapiens, the truly eusocial organism that humans are,
is partially due to the ingestion of serotonin agonists and
now we've had these serotonin agonists out serotonin receptor agonists out in nature that we
are made to feel like we can't use but in reality they're an inherent part of our evolution as a
species and um yeah jesse mentioned i studied aging for my phd i studied it in honeyes. And honeybees are the best model organism for understanding social environment on the aging process. And although it's not patentable, there's a lot to understand about how social environment impacts the progression of aging and the onset of age-related diseases.
And psychedelics are also like one of the only drugs that sort of gives you a feeling of connectedness and social integration chemically rather than, you know, going on meeting people.
receptors that are important in physiological processes that can deter aging at the cellular
molecular genetic level, but also at the social level, which is insanely important for humans,
because it's one of the things that makes us human and to be able to attack or not attack,
but like to be able to address that need of humans for health is another important aspect
of psychedelics.
I really hope we can fund studies into other model organisms
that can get us closer to this, as well as humans.
I think the founder of Research Hub wants to study defective psychedelics on chameleons
because their skins change color a lot when they're under the influence.
Yep.
Yeah, so, yeah, that's a what makes this research being done on pump science
novel in like the long story field of psychedelics like why is it for this year
yeah i mean there's these two papers that came out this summer one showing that lst extended
longevity and c elegans and another one showing that lsd extended longevity in c elegans and
another one showing that psilocybin uh deterred cellular stress uh uh preserved telomere length
and also increased lifespan in mice but this is the first time they're going to be put head-to-head
same conditions in a you know a stepwise model series we'll look at we'll replicate some of the
biomarkers that
these other papers looked at, but hopefully expand it in mice and to give us a good idea
of what to look for in humans, either through some sort of decentralized microdosing trial.
But there's also a ton of blood samples in psychedelic labs that has just been collected
as part of standard bio sample collection and studies that just need funding. And inside these blood samples, sitting in freezers around the world and research labs
are biomarkers of longevity that only need a little bit of funding in order to tease
out.
And it's just data waiting to harvest that maybe we can use some of our funding for, you
know, if we make them raise enough money from the trading fees if token holders want us
to go in that
direction. But ultimately, the novelty of this is the head to head challenge, the longevity angle
and the community involvement. And obviously, first, I could have some pump science.
Yee-yee.
Yeah, I know that we're super excited to see the results of that I think part of what we talked
about you know what you guys opened with was like the stigma of these two compounds and what I think
is really cool is that you know a platform like pump science and the research that you guys are
doing on the platform can be a huge part of changing the stigma around these compounds. Like there absolutely is a place
for them in honestly, like modern medicine, and they've just been pushed to the outskirts for no
reason. And people should have a way and a substrate to test compounds for scientific
legitimacy and bring them to the forefront. So I know Brian Johnson tweeted about, you know, shared a tweet
about recreational drugs for science and being longevity friendly. And that is real. But up until
now, there's not really a way for people to actually go and get the data for themselves. So
it'll be really cool to see. I also, Jesse, that research hub experiment sounds really cool with
the chameleons changing colors.
So yeah, probably an experiment type we can bring forward.
But I mean, I think the biggest thing here is that this is, these are two really cool
compounds, but this is really legitimate science that will be pushing the, you know, the body
of evidence behind these compounds forward.
So I'm really excited to see the data come out from
these. Do you guys also, I know you mentioned like human studies, is there any sort of like
affiliates or anything that you guys have for either of these compounds?
Yeah. Researchers?
Researchers and for the actual human, the distributed human trial.
Right.
They're just coming back simultaneous.
Yeah.
One of our, one of our, one of the core members of SideAl, Balazs Tighetti, he published a study in 2021.
That was the first time they figured out how to do a citizen science self-blinding microdose trial.
And they're now running the second iteration of this right now.
And the PhD student who's running it as part of our degree is also a contributing member
of Side Out.
And we may even be considering funding her, you know, aside from pump science, but there
might be a really interesting way of funding her work through for the purpose of progressing this into a decentralized human trial such as that.
And I think that's where it starts to get really interesting, right?
Is not only gathering data through the gauntlet that pump science has built out of worms, flies, and mice, and then maybe chameleons, but also simultaneously
doing a large scale distributed clinical trial, building on that foundation of Arrowhead and
BlueLight and all these other amazing early internet platforms, and bringing that into
the 21st century of on-chain token incentivized encrypted patient data collection through people buying
legal LSD and psilocybin analogs where permitted, right? Because the regulatory status is very
different in various countries. Like there's some countries that you would literally get the best sentence if you bought and tried these and there are other countries where there's no issue at all
and you can buy them in stores um and so that that's where to me it starts to be really interesting
is people buying these similar compounds trying them and submitting data for a large scale data set on their effects.
And so, you know, we're very fortunate to have affiliates, as you said, Jillian, in
NootropicsDowl and in a store in Berlin called Amama that's quite famous for selling LSD
selling LSD analog called 1S LSD.
analog called 1S LSD.
And if you have followed the nootropics now on Twitter,
and I'd like to let them speak for themselves,
you'll see that yesterday they announced a website called free lsd.xyz.
And if you go to free lsd.xyz,
what you'll see are these compounds, these LSD analogs or derivatives,
or whatever you want to call them, that you can buy with your LSD tokens.
And you'll have the same thing with Silo.
Of course, there's geo-restriction for the buyers so that you don't buy it from a place where you're going to get put to death for getting it or something lesser but still a terrible, kind of the opposite of the intended effect of longevity.
And I think through that initiative, we will have some very interesting data that comes up.
And I couldn't be more excited about it.
So thanks to Nootropic Style.
You guys are amazing.
We love your hustle.
It seems like you're 24-7 on the grind.
And I applaud it immensely.
They are 24-7.
They are 24-7 on the grind, I assure you.
Is that the pineapple on?
I was going to say, that's the hack right there.
The hack is drugs.
Who knew?
We all knew.
But yeah, no, massive shout out to you guys for kind of like memeing these psychedelics. And I think that's important to study.
But also like a lot of the stigma around drugs is that they are quote unquote bad for you.
Right.
And like, what does that even mean?
If these drugs extend your life, like how can they possibly be bad for you? Like health wise.
So, of course, there's like the psychological component to study.
That's important. But, you know, I think like health, like like the stigma that they get for being unhealthy, like drugs are just, you know, kind of thrown into this bucket of like some stuff that's bad and what the truth is. So appreciate you guys and your work so much.
I think when I first talked to Paul Kohlhaas, the founder of Bio, and he was trying to get me
into the DSi space, one of the things that really convinced me was, so both of us are
avid ventures onto the research chemicals subreddit, which is probably similar to like the blue light form that you guys are talking about,
where people are just taking random shit and just testing it on themselves
and reporting their subjective results.
You know, there's so many random compounds on there.
And at the end of the day, all of these are end of one experiments.
And that's such a shame because, you know, I'm sure many of these are very powerful, you know, both in terms of the experience you can have and potentially on, you know, your health, like we don't know. consciousness and then being able to like run studies on them just to find out together what
what does what you know versus just like you know expecting anything useful to come out of this
like disparate n of one studies so i don't know what you guys think about that yeah actually i
had a question for you with your background in those forums is there you think a way to compile
some sort of like at-home biomarker kit that
could be kind of the next step of home science, where if it reaches a certain amount of,
you know, market cap or whatever, then these kits are deployed out to people who want to
involve token holders, whatever, in order to standardize the collection of these biomarkers
in terms of taking these substances?
Yeah.
So we've thought about this a lot
and I think that the easiest thing biomarker wise will always be. And basically when, when,
when we say biomarkers, it's basically just anything you can measure, right. That will
kind of indicate whether a compound is working. So a biomarker could be your heart rate, it could be
your blood pressure, it could be, you know, it could also be a subjective experience, you know,
like, do you feel happy or sad, like that's a biomarker as well. So I think ultimately,
the easiest biomarkers to collect at first are going to be the digital ones, right? So
the first human studies that we're going to do are going to be with wearables so
you just wear your aura ring your garmin or whoop band or whatever and we collect all of the data
that those can capture just because you know people wear wearables already um it's very easy
to integrate with that data there's no extra cost associated with it even as like a participant in
the study you don't even need to change anything you're
doing.
You just need to set up the data connection and then you're good to go.
So we'll probably start there.
But in terms of like where it gets more interesting, especially with nootropics and psychedelics,
because obviously both are brain focused.
I think that, you know, questionnaires, exams get super interesting.
Like, like do psychedelics make you dumber?
Like we can answer that question.
And, you know, it comes with, you know, some sort of like standardized test to test your
cognition, you know, pre and post, you know, taking a psychedelic.
I'm super curious about that.
Does it make you smarter?
Does it make you dumber?
Does it make you more chaotic in your thinking?
Like, what does it actually do for you to your brain? Because it's very difficult to tell as, you know, a participant, but it's super easy to measure. Right. And so rather than just like take stuff and subjectively report back, which is what you see on all these forums. Nobody's measuring anything other than just looking inside
and seeing how they feel, which is obviously kind of hard to measure.
So I'm excited by when Nootropics now is building with their Nexus,
where basically people can take tests,
and you can kind of measure your reaction time and your working memory
and your time perception and things like that.
And then we can just take all these different nootropics or psychedelics and see what they
do to people's scores and then just actually measure what the hell they do. So at least like,
you know, we can start to get actually objective data rather than just like, oh, I feel a little
better. Yeah, that's really good.
We might be able to integrate that with this research survey platform that we're developing
called Opsi, where it's like a token for data, data collection model, working with psychedelic
researchers to develop assays just like that that are focused on the effects of psychedelics
long term on cognition, happiness, all that stuff.
I'm not sure if this thing is working.
I've never used this basis thing before.
It is.
I can hear you.
Oh, fantastic.
Fantastic.
I'm actually working on measuring cognition in drug users.
I have a paper in review at nature communications at the moment
on my super large scale data actually across all sorts of like naturalistic types of drug use and
i'm working on software to be deployed that's i don't know everyone's phones for being able to
measure their own cognitive ability in real time i've literally only clicked on these spaces because
i saw drugs and i have 10 minutes until i have to leave the house and I was like well let me see what everyone's talking
about but it's actually so on topic for me I'd be very interested in talking
more to people about this because it's something that I'm focusing on every
single day so yeah well you know they say that coincidence is the engine of the universe. Like mutation, evolution, the position of the earth.
It's all coincidence, really.
Yeah.
So you being here now is one of those engine moments.
Yeah, I'd be very interested to continue the conversation on this topic.
I mean, so far, the project that I'm working on,
we've been very lucky to be working with a very large-scale cohort
from the general population who's not recruited from drug use forums.
I actually have quite a bit of criticism on the bias
that can come from specifically targeting that.
I'm very much interested in general population studies
where people have a range of different experiences, not necessarily
those who had positive experience that are keen to talk about that or the other extreme, you know.
And I can tell you that we can identify that there are distinct cognitive fingerprints,
both in the short term, so immediately after people take various substances, including psychedelics,
and long term. So I find associations with like
one-off lifetime uses, for example, that are on 0.2 standard deviations, differences relative
to drug naive people, which is basically at population scales, once we're talking into tens
of thousands, that's actually quite significant. So this is the type of tech, we've developed this
software basically for academic purposes, but it's the type of tech, we've developed this software basically for academic
purposes, but it's the type of tech that I'm working on, essentially transitioning to put
into everyone's pocket so everyone can take the test in five minutes and monitor their own cognition
and so forth. Very interesting collaborating on blockchain opportunities for this, by the way,
because I'm a big believer that everyone should actually own their own data and so forth. And us scientists just have access to aggregates so we can do, you know, machine
learning models and so forth. 100%. That's why we're all here is to like empower each individual
person. That's fantastic. I don't know how I ended up here, I swear. Yeah, thank you so much for
joining. Thank you so, so much. But like, yeah, I think the way to think about it is you are building the tools to answer these questions and we want to build the incentives.
All right. So that's what crypto is all about. Like all these tokens are at the end of the day
is, you know, like an incentive engine. Right. And so, you know, you have to think about whenever
you run a study with people, you know, if you run it on mice, you know, you even need to give them
food or some reward. And so like these tokens are kind of our equivalent to try and incentivize people to take these studies,
regardless if they had a good experience or a bad experience, but just to share their experience, period.
So Dr. Ballet, it would be amazing to be able to talk to you maybe over DMs in terms of.
Yeah, I'm happy for everyone to DM me. I literally need to go to see my grandma in 10 minutes um but yeah basically i uh i'm very interested in discussing more about both the
research i've already conducted and different opportunities to collaborate with all sorts of
organizations especially um if we have a shared goal of making sure that the individuals get
access to the data and own the data about their own cognition
and can make more informed choices about, I don't know,
like let's say someone wants to drop acid at the weekend,
but then they notice that when they log a diary,
their cognition doesn't function as they want it for a particular event.
Well, maybe they can make their own informed choice.
Next time, don't drop it before the day that you have to do this thing,
or maybe they help with something else.
So this is the whole ethos that I'm operating under and want to build on.
So, yeah.
Totally.
And I think one other question I'm really interested in answering, just like having subjectively experienced it, is like post,
they call it like, I think post like, post trip glow,
where basically you have an incredible sleep after taking psychedelics, and you wake up the
next morning feeling incredibly refreshed. I'm super curious whether you know, the time of day
that, you know, they're taken, whether or not that impacts the sleep and how actually
impacting the sleep affects the cognition the next day when these tests are taken.
So I think all these are super important questions that can be answered.
And yeah, if you don't mind DMing us because it looks like your inboxes are closed, please,
please shoot us a DM.
We'd love to figure out how to integrate your technology.
And yeah, we can offer it as one of the,
basically studies on our platform.
That's very kind of you.
I'm very happy to hear that people have an interest in this, honestly.
So yeah, let's chat more.
I'm going to have to drop off.
I literally have to go to see my grandma.
But yeah, I'm very happy to have clicked on this.
It's very cool.
And yeah, I'll try to to have clicked on this. It's very cool. And yeah,
I'll try to be in touch in the next weeks. Amazing. Yeah. Well, please send us a message.
And if you also want to join our Telegram, we're also really active via chat in there, but we'll be on the lookout for you. And thank you so much for dropping in. I would say, guys,
that's the power of sharing the space is it gets to more people.
So if you haven't already, please reshare the link to the space.
Let's get as many people in here.
You never know who's going to pop in.
And little known fact, but that's the advisor to our science communications lead, Preeti.
Follow us on TikTok to see her communicate science in a very effective way.
For sure.
Yeah, I've seen what you guys are doing on TikTok.
Preeti is amazing.
So way cool.
Awesome.
So I know we have some other drug devs on as well from other compounds that launched.
Would love to give you guys the floor.
I know we also had some new ones
that launched this week. We had a big pharma. Was there a compound that you guys launched?
Did you guys, I think you guys launched boobs. Does that sound right?
Oh, sorry. My speaker cut out there.
Yeah, we did.
It's a stradial.
So, you know, we, we were kind of going
for the more mimetic side of things,
but still an interesting compound, obviously.
You know, it's, it's actually more than just mimetic.
I know, I know you were just going for the meme,
but kind of as Jesse said of like coincidence is the fuel engine of the universe or whatever.
So there's this study called the ITP,
the Interventions Testing Program,
which we're basically trying to compete with,
add to whatever you want to call it.
But their top performing compound
is a derivative of
estradiol um it's called 17 alpha estradiol so um actually not that memetic just want to say like it
coincidentally you actually almost just picked the top performer in the itp
yeah actually uh 17 alpha estradiol is the is the one that we're going to be testing.
So, yeah, I mean, you know, part memetics, part real life.
I mean, that's kind of what we're all about, right, is like, you know, big boob anime girls, but also real science.
So that's our niche, definitely.
But, yeah, no, we're super excited to see what happens
and um we are actually we are fully funded for mouse studies um and because um estradiol is not
uh a sex hormone or or supplies um we're just going to strip skip straight to mice. So that should be coming soon. Yeah, one thing to kind of remind people of is,
so if you launch a compound on pump science, the fees go to funding the research. So if there's
enough fees, you can do worm studies, fly studies, mice studies, and then hopefully here soon,
decentralized human studies. It's up to the drug devs to really decide the
research path. So some compounds are doing multiple worm studies. Some compounds are,
just as Big Pharma mentioned, going straight to mice. Also, people are bringing forward different
ideas. So LSD, SideO, the team has brought up the chameleon. Maybe that's something that we can do,
but we're actively working with drug devs to really find the best pipeline and path forward for research for their
compounds. So don't feel limited by what you see on the platform today. If you have an idea,
a study you want to do, bring it forward and we'll work with you to really try and find a way to bring
that to life. Yeah, no, it's awesome. And we actually, we bonded before the dynamic, the dynamic AMM fee was,
it would bond it at like 60%. So we got a lot of fees. And then on the chameleon studies,
just want to add, I actually did a chameleon study like that when i
was 15. um very uh why did you give your chameleon what just uh just weed nice but uh it sure did
change colors probably not that it did but yeah oh yeah big time did it turn green it's already uh it turned it was like it was like green and purple and like it
was totally wild uh not the nicest thing to do to a chameleon but you know are you sure it's bad
though because we were thinking that like these mice who get tested with this lsd in the
silo they're gonna have the time of their lives like they're gonna have the best experience of
any of the lab mice with any of the compounds uh true true i i hope that's right i do know so
there is a study i can try and surface it it, that I read a few years back.
So this could be wrong, but going off of long-term memory here,
which is kind of shot over the last few months of not sleeping.
You've got to try to pinealong.
Yeah, yeah, yeah.
Nootropic style, can you ship me another box of pinealong, please?
But yeah, so what they did was they took mice mice they put them in a cage with two different um
like water vials and one of the water vials had regular water the other one had cocaine water
and as soon as the mouse um drank the cocaine water it never went back to the regular water
water, it never went back to the regular water. But they did the same thing with acid, with LSD.
And as soon as the mouse tried the LSD water, it never went back.
You know what they say? You only need it once. And that's why it hasn't been commercialized.
Because our models are still dependent upon prescription recurring revenues and that
just doesn't come from getting one-shotted that's so true also um correct me if i'm wrong but i i
think this is true um hoffman like alfred hoffman i think is the name, who discovered LSD. He lived to like 103, 102, something like that.
Yeah.
Coincidence?
So, no, there are no coincidences in this life.
There are no coincidences in this chat, at least.
Speaking of animal models, there's a pretty famous research
at Johns Hopkins
who gave Molly to Octopi
to study their social behavior.
So there's precedence for...
This is the craziest study ever.
Do you want to talk about it?
It's fucking wild.
Yeah, wait, I need to hear more.
Yeah, basically they had a tank
that was divided in two
and in one of the tanks they put MDMA and studied the positioning of the octopus.
And the octopi that were given MDMA always were closer to the division in the tank where they could see the other octopus.
So as a measure of social behavior, like wanting to be around others they found that
when you give octopi mdma they just want to be with other octopi which is tracks if you've ever
taken mdma you just want to be like touching other people and all that jazz um so there's
precedence for this and studying these sorts of things in non-traditional animal models that is
super informative wait i think i don't know if this was the same study and maybe just like a different experiment
or a completely separate study but the one i saw they gave mdma or control to um to octopi
and then they would take another octopus and put it in like a like a bad situation, like put it in a jar or yeah. Or like a situation where it needed help.
And the octopi that took the MDMA were more likely to like help out the
octopus in need, basically.
Like there were more.
They did a few.
I think they've also, they also did some physiological measures.
I can't recall what they found off of that,
but it just aligned with the behavioral stuff like that.
It's, it's really insane.
Octopi are super intelligent as anyone who knows about animals knows.
One other super interesting thing about that study is that it makes psychedelics go beyond the brain
in terms of why it helps us and makes us happy and connected and things like that.
Because everyone likes to talk about what mushrooms or MDMA do to our brains, how they turn off the amygdala, they make you less fearful,
and that allows you to connect with other people. Well, octopuses' brains are totally different
from us. They have three brains. They don't have one brain. And yet MDMA did something that was so
similar to what it does to us that there's something about the way MDMA works throughout your whole body and throughout your whole system that goes beyond the brain.
And so it turns these magical drugs into something that's, again, not that's throughout the whole being.
And we're just seeing that throughout the whole animal kingdom, we have more in common than maybe we thought we did.
So that's just one of the many things that psychedelics have really shown us.
Again, our connectedness to ourselves, to each other, and to even other species.
Hell yeah. And that would be a sick live stream.
Yeah.
It could start to get a little risque.
I wonder what the cocaine octopus would do.
It would just strangle its friend.
Yeah.
So fucked up.
No, the cocaine octopus would pitch you a business idea.
It would sell the octopus a ticket out of the of the jar okay there's something about this octopus
conversation a ton of people are requesting to speak so if i brought you up feel free to chime
in but people are loving the octopus keep keep the tentacle porn comments to yourself.
Crypto-thon, you want to speak? Yo, wait, wait, just last thing.
Have the PsyDaw guys seen the study on various different drugs
and what they do to spiders and their webs?
Oh, yeah. on various different drugs and what they do to spiders who and like their webs oh yeah it's one of the most it's one of the more famous memes related to drug science so there's a famous
image that's been circulating the web since like the early days of the internet showing in uh tile
format six or seven different spider webs that spiders made while under the influence
of various molecules and um the webs created by spiders on
cocaine were very different from the webs created by spiders on lsd
the the cannabis one's hilarious like clearly it just gave up midway through
it's just like yeah it's fine i'm gonna tweet out the image now uh if anyone wants to see it
just go to our page at pump psi p-u-m-p-p-s-y i'll pin it here too
and i want to put in the obligatory reminder about set and setting, because one of the things those octopus studies showed is the way that the cells are reopened to new growth.
And the directions that our bodies regrow when we have this reopening on psychedelics
depends on what's around us when we're tripping.
And so they found that if you put animals in a more happy, safe environment while they're tripping,
their brains regrow in a healthy way.
If you put them into a fearful environment, their brains regrow in a healthy way. If you put them into a fearful environment, their brains
regrow in a less healthy way. And so it's just revalidation of something that
psychedelic people have known for hundreds of years, which is if you can,
when you're taking psychedelics, put yourself in a good environment, happy
people, supportive environment, nature, good music, good food, all that kind of stuff. And your brain really will regrow in a more happy, healthy way. So I don't know if we can get these flies,
some good music and maybe some disco balls, maybe some beanbags, but we'll talk to the CRO about that.
Try to get our mice.
Good vibes only.
Yes, yes, yes, yes.
Good vibes only.
Real quick too, just to let folks know,
please keep requesting to speak.
I'm rotating out some of the speakers.
So if you were up here and you got moved to the audience,
it was just to make room for some other people.
But if you have a comment,
please feel free to request to come back up.
But we have Black Bowl, you have a comment, please feel free to request to come back up. But we have
Black Bull, you're up here, and we have, let's see who else, Boruto, feel free, Martin,
feel free to chime in. Welcome.
Thank you so much for this space
yeah tell us about yourself working on are you are you guys working on longevity
oh yeah that's the the whole reason why we're here. So pump science, are you familiar with pump science? Yeah, yeah, yeah. I know.
Okay. Okay. Yeah. So we're, we were just talking about different studies that you can do. It
started with octopus and then we started talking about spider webs, flies, but looking at different
science that you can do to not only understand longevity, but the effects that compounds have
in other, other types of studies
is there a compound you're interested in
i know about and i have a question why all of the research are doing on animals like rat like cats
and do you really think if something happened to cats, it will happen same way to the human body?
Is my question clear?
Yeah, so your question was why test on animal models?
Is that correct?
Yeah, yeah, yeah.
Why always the whole world's research based
on animals like cats like fish rabbit why because human are different that's right and there's like
is there an injustice there in testing on all these animals if that yeah if yeah if something happening to rat rat biology is different from human
so why i could speak a little bit to this um yeah i mean obviously all animals are related to us in
terms of the timeline of evolution by natural selection. So we have, even though we have different physiology in some ways,
we also have very, very similar physiology in most other ways.
Genomes are many.
Which animal is close to our physiology?
Most closest to our physiology?
Which animal?
Sorry, actually, my sound is a little shaky, so I couldn't hear the question.
He wanted to know when he was asked.
Hello.
Sorry, guys.
Actually, I have to leave and come back in because my sound is off.
I'll be right back.
Only a matter of time before Twitter rags.
The gauntlet of pump science, and correct me if i'm wrong please jillian and benji
is designed to progressively get closer to humans in physiology so you start with
c elegance and then you you go to flies and then you go to mice and then from there maybe chameleons
or humans and as you progress through the chameleons the hardest I've ever heard him push anything. I want to see them change colors so bad. I feel like that will be
such amazing content and I don't know. Okay let's acknowledge that this is for the content.
Well I don't know like personally I sincerely believe what I said earlier that these mice are
going to have the best experience of any lab mice and then it's really a blessing that we're able to offer
them LSD and psilocybin when they've lived their lives in confinement in these laboratories. They
get this moment of transcendence and beauty. Jesse's going to be reincarnated as a mouse
in our lab study. He's going to be in the LSD study, but he's getting the control.
I hope not because i'm
seeking nirvana in this lifetime which means no reincarnation beyond it
no but i think martin to your question you can think of it like a computer like we offer
the the research protocol for pump science is worms flies mice and then ultimately uh humans
and then potentially some other animals
in between. But part of why they're the various animal models is because how do you know,
ultimately, what is, you know, worth testing in humans and in the big computer, if you will. So
by offering something like a CL, again, you can think of it as like a microprocessor,
or really, really small computer. That's something that doesn't
live a long time, um, has cells that are similar to humans and you can use that to get an early
read and each animal model progressively becomes more similar to humans in the, in systems and
cell types. So, um, you get more data to then help you understand which ones are ultimately
worth going right into humans, as opposed to
doing the studies right into humans when you, you know, it may or may not have an effect,
but really using that body of evidence to help make that informed decision. So a lot of times,
people have said like, why worms? Well, the worms really, you know, are a relatively inexpensive
experiment. They have systems that are 35% similar to humans
and they don't live a long time. They live about 28 days on average. And so you can get a lot of
information on, you know, by doing those early studies in worms to see if there's, you know,
a hit that warrants doing the study, the more expensive study, the animal models that live
a bit longer to ultimately progress it to humans. But we aren't in the business of slowing down
science. So we don't, you know, if you launch a compound on pump science, and you have funding,
and you want to do the experiments and worms, flies and mice, and you have the fees to do it,
the drug dev is certainly welcome to make that decision. But that's a bit of the rationale is really giving you that body of evidence to
help make an informed decision when you get to humans.
I think another way to think about this is we're trying to maximize life in the universe. And so
you start with things that don't live very long and you test on them. And if it extends their life, then you graduate it to these animals that live a little bit
longer and you see as they extend their life. So it's like, how do we maximize the amount
of time for all living organisms? You know, that's that's kind of another way to think
about this protocol. Anyway, we've got some hands raised. I think Crypto with Karthik,
I think you had your hand up first.
Do you want to talk, boss?
Oh, yes.
Thank you very much.
I just wanted to directly answer the previous question, as I'm kind of an expert on animal
models and experimentation, clinical experimentationclinical experimentation for the actual field.
And the main reason you don't want to test things on humans first, because, well, first,
because it's illegal and it wouldn't be ethical
because you don't know whether what you're testing
is going to hurt a person or not.
So before trying something on an actual human being,
you've got to test this on animals
to know that it's going to be toxic
and to know whether it's going to be toxic and to know whether it's worth to be testing
humans as you need to produce data that will convince the federal agency to approve human
experimentation. So sometimes it's very tough to get approved for human experimentation and you've
got to produce a lot of data on animals. So animal experimentation is vital to developing any kind of drug. So
it's a very vital part of their development. And if you're concerned about animals getting
armed, there are specific guidelines, there are specific ethic committees that have to
prove that your experiment reaches the standards for animal care.
And that's the main reason you don't
want to read something on humans first.
So it's about ethical guidelines.
And with regard to our compound that we are developing
on Plum-Blo-Science, which I'm very excited about, which
is BPC-157, we are kind of in a really particular spot,
because we already have a lot of data from humans
because these compounds have been tested within the bodybuilding community, within the fitness community.
They've all been hacked in kinds of human lab rats.
However, the data we are producing on those small organisms, on the animals, with Pantoscience,
is data that didn't exist before.
So as a scientist, I'm extremely excited to see what those compounds do to those small creatures
because this data doesn't exist.
So producing data that doesn't exist is extremely exciting for me as a scientist.
And we can also study the broad effect of this peptide,
of these peptide seeing that if it has an effect on different life forms then it means that there's
seeing that if it has an effect on different life forms,
like some pathways that are highly conserved from those organisms to humans so we can also study
or these very interesting connections so that was it'll be cool to see how the science moves
forward for sure and like you said there's a way that you can
generate data that's never been generated before. Also want to give the floor to some people who have their hands up. Let's see, Crypto with Karthik, did you have a chance to speak? And
I'm going to rotate out some of the speakers to get some other folks up here. All right, let's see.
I don't think it's worth working for Karthik.
If he is able to unmute, shout, but you want to bring up Alec,
and then we can have, who's this, Ginsenicide, RH2.
Yeah, let's go.
Are you at ARDD?
Yeah, hi, Benji.
I'm at the ARDD.
So I'm joining from Copenhagen, Denmark today.
And that's why I have less time to talk here.
But this is the world's largest conference in the longevity research.
So, yeah, very, very much new science is being presented here.
And very happy to be here.
Amazing.
Please chill us at
every opportunity if you don't mind yeah definitely so my name is ashish rajput i am based in germany
and professionally i'm a scientist i'm working on three compounds at pump.science because i think
they are like really promising in the promoting the lifespan and healthspan.
So that's why we are testing it at FAM.Science.
The first compound is called, these are first of all, derivatives of ginseng.
So ginseng, you know, this is like very safe molecule tested like from last 2000 years.
Chinese and Japanese people are using it as a
longevity compound. And we are testing like individual components or individual molecules
from them. So first one is called GINCH2 or Ginsenocyte RH2. It is working as a guardian for
our DNA. It prevents from DNA damage, prevent our mitochondria, and then rejuvenate our
whole cell. So it is also showed 27% lifespan extension in worms, and it's already funded for
the fly study. So I'm waiting, yeah, really looking forward for the fly study to start as soon as possible
then second one is ginge one it is also a amtor inhibitor molecule and it also works in like it
it works more in the sense like in the long long living species for example flies mice and human
it will be showing much more effect compared to less living studies animals and the
third one is called beast it the name is coming from because it's a molecule coming from broccoli
as you know broccoli we all eat for the healthy longevity molecule is called sulfofarine so it's
coming from broccoli but it is also known as DNA damage protector it help our DNA from
all this damage happening from environment and so on so it also showed 25 24 percent life extension
and worm study and it's also funded for the fly study and I'm also looking for that. The last one is wrong.
Beast is not funded yet, but I'm looking forward for maybe more
investment into that, and then we can do also on the flies.
Thank you very much.
Dude, of course. Thanks for hopping on. Enjoy the rest of the conference.
Thanks. I hope it's awesome.
Anyone else want to talk? I don't know if I've seen any hands raised.
Alec, I saw you with your hand raised. I don't know if you were able to come up.
Yeah. Also, it's brand time. I know you had requested to speak.
Tried to bring you up and it wasn't working. So feel free to try again.
bring you up and it wasn't working. So feel free to try again.
You know, also, also Guumpy, we should get you up here,
hear about your experience in the hospital. If you don't mind sharing with us.
Yeah. If you want to request to speak. Yeah. Who do we have here?
You know, one thing that we haven't talked about too.
Oh, let's see if Guumpy's coming up. Alec, let's see. Got you back about too, let's see if Glumpy's coming.
Alec, let's see, got you back up here.
Let's see if it worked.
I've got limited service, so I apologize if I'm coming in all broken.
Can I get a mic? No, it's good.
It's working.
Loud and clear.
GMGM.
Hey, Benny.
Nice to see you again.
I don't know if you remember me, we we chatted briefly at the pump science fair
at accelerate oh shit what's good oh my god sorry i did not write it it's okay it's okay i'm glad
to see you guys are still grinding on this but um you know i i popped in i think at the right time
because someone asked about longevity and i'm not showing another project, but I was in a Believe space just yesterday when someone
that is, I guess, based in Sweden or Seattle, I think they're called Innovance or something like
that. Did we lose him? Yeah, I think we lost him.
Did we lose him?
Yeah, I think we lost him.
Alec, if you're out there, request to speak.
We lost you.
Right at the good part.
What a cliffhanger.
I know.
I'm looking up in advance.
I don't see shit.
Okay, I think he's back.
Oh, he's back.
Alec.
I'm back.
What did you say it was called?
I'm going to try to find it for you without rugging myself.
But they were believed speakers yesterday on their weekly host or spaces.
It was called Innovescence.
I-N-N-O-V-O-S-E-N-S-A-B.
They're a Swedish-based company.
I think that they're primarily tokenizing due to the ICM meta.
And they have non-invasive
I guess products that register or read
test levels,
glucose levels, and I think that they're on
chain data as well. And I feel like that would be an
interesting intersection or conversation for you guys to start. I have no relationship to them or
relationship there. But when listening yesterday, it sounded like that they're pretty far along
in their product drop or delivery and thought that there's some way that there might be some bright minds on this side
to connect with their bright minds on that
side and see how there can be
additional testing to move other
non-invasive
I guess products into
what your guys'
current research is.
You are a legend. This is so
sick. I will 100% hit hit them up you're the man
yeah no no problem and i had nothing really more to say other than you know i'm really excited to
see that despite it being a pump fun project which a lot of people you know have speculation around
that it's really great that you guys are continuing your charge and are developing you know really
interesting testing experiences leveraging the lives and doing all the things that you're doing to like actually make science happen on chain.
Amazing. Yeah, no, no. And like this, what this group is building in NovaSense is like exactly what we want to power things like human studies.
So it looks like they have an app where you can just like integrate a shit ton of biomarkers
um and yeah i mean like that's that's kind of what we need to integrate with to uh to enable
people to like speculate on those human studies right like that's essentially what we want to do
it's like you know some psychedelic gets launched or some longevity drug gets launched um you know
some longevity drug gets launched. You know, what does it do to people's various like, you know,
heart rate, sleep, blood pressure, et cetera. And that seems like what these guys are building. So
we'll definitely hit them up. They seem like slightly competitive with Pulse, who we've been
talking to. And there's also another one called CUDIS, C-U-D-I-S. If you want to check them out,
they're building like an aura ring on chain. So anyway, I'm excited to see which one of these is like the best and, you know, kind of goes viral,
but we want to integrate with them all. Super, super cool. Thank you so much.
Thank you guys.
Hey, so I have a, thanks guys for having this space. this is the first time i'm hearing about all these
projects i think it's very cool to bring science on chain so my question is this um i in my personal
life i have a lot of connections with uh scientists who are working on um uh think things like
oligonucleotides for different different diseases as well as working on just various like
rare genetic diseases and they don't know anything about crypto they don't know how that works at all
i'm just wondering is what you guys building a platform for me to kind of bring some of what
they're doing on to you guys and see if they can get some funding that way would that be possible is
that something i should look into um 100 so first of all i don't know if raptor is still on the call
but um what he is doing is building like a rare disease consortium so um they're basically trying
to be like a central like shelling point for, you know, various different rare diseases so that, you know, like if, you know, obviously rare diseases are rare, like it's in the frickin name.
So there's not very many of them. But if you pull all of them together, you can kind of like be the place that everyone goes if they have a rare disease to like crowdfund cures together.
So that is what I think it's called Curetopia is focused on.
And the founder was actually one of the speakers here, but he may have left.
So I would definitely have any of your friends who are looking at rare diseases to check
have any of your friends who are looking at rare diseases to check out Curetopia.
out Curetopia.
But if your friends are interested in testing their oligonucleotides on all the different
animal models that we're testing on, they can absolutely submit them to our platform.
So they would have to like basically say what they are because, you know, everything here
is kind of open source.
But if they're willing to share what those oligonucleotides are and are able to like source them,
then, yeah, we can send it to the lab and have them tested on the different animals to see what they do to their lifespan.
Do they have, you know, efficacy? Like what do they do to mice and whatnot?
So, yeah, they can 100 percent get stuff tested here. That's the goal.
Sure. Thanks for the answer to that. And again, this is the first time I've ever seen something like this. Obviously, you guys have all been around for a while. I've just never run across you guys. But I just want to say this is what crypto is for. So congratulations on everything you guys are doing. I'm looking forward to learning a lot more about what you guys do.
Thank you so much for having me.
You're a legend.
And honestly, it's just a show we're so bad at marketing.
We're just a bunch of nerdy science losers, and we're ass at marketing.
So thank you for finding us.
It's a testament to you, not to us.
Yeah, I'm shared your Twitter handle
in the Pump Science Telegram with Ethan, the guy that Benji was talking about. So if you're not
already, I would join the Pump Science Telegram. And there's a channel in there, Raptor, where
that drug dev is super active, the guy who submitted the raptor um token which is two compounds that are
being tested on pump science so get in there he's he'll be on the lookout for you but he would be a
great contact as well but a great place for you guys to connect and gave him a heads up cool beans
yeah yeah and to piggyback on that like you know you know people, tell them it is so hard to get scientists interested in this and to understand that it's real.
Like, my sister is an amazing molecular biologist at a leading university, you know, not doxing, obviously, but, you know, I'm having a hard time convincing her to join.
I'm having a hard time convincing her to join.
So like every,
every legit scientist who joins is like another step toward really making this
thing work.
So like tell your friends and tell your scientists friends most of all.
Yeah.
And we are talking to some extremely legit scientists. A lot of it,
we have to keep confidential until like the time is right, but really, really excited about some
of the scientists we're talking to. A lot of them you probably know are like very mainstream names
and the bio team also. So what, you know, putting your name out there gets you is like the credibility to get in front of these people. And they're all very interested. I think, you know, putting your name out there gets you is like the credibility to get
in front of these people. And they're all very interested. I think, you know, we've talked about
like, okay, who actually gives a shit and is bullish on DSI? Like, even the most traditional
scientists are starting to realize like they have kind of hit the ceiling in terms of what they can
get done in the current system, And they're getting sick of it.
And they're like, OK, what are what are other opportunities to get funding to do more science
and to actually push forward the ideas I want?
Like many of them have to do the research that they can get funded by grant funding
based on whatever the hell that person who's dishing out the grants wants to see, but they often cannot actually do their best idea.
They just do the idea that they think will get funded.
So this really liberates them to actually study their best ideas.
And if you think about it, like scientists are upstream of everything.
Like it is the scientific discovery that creates,
like even technology is downstream of science, right?
Like in order to make tech,
you need to make scientific breakthroughs.
And then that trickles down and, you know,
it benefits all of our lives.
You know, all these drugs before they became like
an engineering problem of making the drug, it was a scientific discovery problem. the rate at which we benefit as a species, because you're letting the brightest minds
who drive society forward the most do what they're actually think is going to move the needle
versus, you know, just kind of like succumbing to whatever they have to study based on what can get
funded. So this does become pretty game changing and liberating for us all if we can get this right. So anyway,
I'll shut up, but I hope you understand the magnitude of it.
Dude, and I would just add to that. I mean, I'm sure you guys are all aware that the NIH's budget
has been slashed since Trump got into office. So any scientist who's working, you know, with any type of funding from the NIH,
which is like a lot of them that are working in public institutions, they're all freaking out
because all the money's going because Trump is cutting everything. So this is, this could be
like a great, I guess, sort of like lifeboat or sort of... Dude, it's an alternative.
Yeah, it's just an alternative.
They just got rug pulled for the first time.
And now they're like, where do I go?
You know, and it's actually so funny
because in the DSI space,
we spent so much time and effort
trying to get the academics to sign up
and like tokenize their research and shit.
And they were all so averse to it because they were so cushy.
Like the NIH funding was just guaranteed.
And so, you know, they were just like, there was no pain that they were feeling.
They were like, why would I go and accept this new form of money that's super sketchy
and like nobody else is doing it.
And it seems super risky and everyone
says that crypto is a scam that's all I read um when I can just go get NIH money like relatively
easily and they just assumed it as a constant right and then all of a sudden they get rugged
and now they're like what the hell do I do and now it's kind of flipped where they're like, can we please raise funding with crypto?
Like, it's the conversation is totally flipped.
It's like, you know, dating as a guy, like when you're young, you know, girls want older
guys and when anyway, you get the point.
Anyway, you get the point. It's like the conversation is totally flipped. And I think that now is Desai's time to win, like because there's actual pain in the market. And we have a solution. We've been building it for years. And now it's just like the conditions are right to get mass adoption. And so I'm really glad you mentioned that because the timing is key.
It's like the conversation is totally flipped.
And there's yet another important movement that's happening, which is the Make America
Healthy Again movement, which also benefits us because like, dude, we're not pharma.
We're just representing what the people want.
Right.
And so to be able to have a way for the people to exercise what they think should get funded is just like yet another kind of movement that's also benefiting all of our work.
So anyway, the stars are aligning.
It's time to make moves.
Yeah, and real quick, Demo, I replied to the tweet with, with the space, the telegram.
So you can click that link.
Um, it's posting right now and join in there and navigate to the Raptor channel and you'll
find Ethan.
But for anyone here, if you're not already, the pump science telegram is a great place
to go for questions, to connect with the drug devs.
They each have their own channel for the, and drug dev is the person who submitted the compound.
So get in there if you're not already.
Looks like-
Hey, thanks Gillian.
Sorry, I joined and I'm having trouble finding that channel.
How is it spelled?
Like R-A-F-T-E-R or raptor.
R-A-P raptor, like a dinosaur. R-A-P. Raptor. Like a dinosaur.
Velociraptor.
Got it.
Got it.
I'm in.
You got it.
Timo, you're a legend.
Thanks for joining, homie.
Cool.
It's been an hour and a half.
Should we wrap it up here?
Yeah, what a good route.
Back to work.
Yeah, back to the grind.
Yep.
Just a huge thanks to everybody who joined.
You know, this is why we're doing what we're doing to bring science to the people, to give
you a way to test compounds that you're interested in, to give people a way to not only compounds
that you're interested in, but if you're, you know, for the guy who was in the hospital and
wanted to find an alternative or to people who have want to reverse the stigma of a compound
like LSD, for example, this is your substrate to do it. So if you're not already joined the
Pump Science Telegram, there is no shortage of activity. As we mentioned, there was the first
AI agent integration with with Pump Science this week through Big Pharma AI, which was Batty, which is allowing people to use an agent to find compounds to launch on the platform, which is really there's been a ton of science that has launched and more to come.
Telegram and our Twitter is the best way to stay informed. But Big Pharma, do you have something to say?
the best way to stay informed.
But Big Pharma, do you have something to say?
Yeah, yeah.
I just wanted to say, you know, big shout out to the drug devs.
While we've been speaking, the Big Pharma AI DAO
has purchased 1% or more of all of the drug devs
in this chat's compounds.
So we purchased PNL, LSD, Silo,
LSD, Silo,
PC157,
MuriOSEN, and
Jing2.
So, you know, we're here to support you guys.
we love
what you're doing. Just keep it up.
Let's freaking go.
Anyway, you know where to find us.
We're in the telegram
awesome we'll see you guys in the telegram thanks everybody for joining and we'll try and
do it again next week i'm having a hard time hearing you. He sounds like Darth Vader.
Okay, glad it touches me.
Is he blowing bubbles underwater?
Is he talking?
He's with the octopus.
Awesome.
Okay, thanks, guys.
We'll see you.
We'll see you. Have a you have a good one peace bye Thank you.
Host
Speaker
Big Pharmai
from
Big Pharmai
Nootropics DAO
from
Pinealon
